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Our
Mortal
Drugs
  • Looking for the Birth of New Antibiotics
  • David Mogolov
Though these drugs derive from genetically primitive processes, it is beyond our current ability to invent them: we can only synthesize and modify them once we’ve discovered them. Discovery at such a miscroscopic scale, it turns out, is hard to come by.
We should be rooting for teixobactin, because we need new drugs. The danger of a world with unchecked antibiotic-resistant infection is the stuff of dystopian fiction (or, if you only have 15 minutes, an early episode of the podcast
"Meanwhile in the Future").

Our relationship with antibiotics and bacteria will never be a settled one. Bacteria will continue to adapt and thrive. If we want to do the same, we can’t forget the mortality of our drugs.
The germs certainly won’t.
David Mogolov tells stories on stage. His new monologue, Clenched, will be in New York City and Boston this winter. He also runs Out of Stock, a site where new works are created from odd stock photography.
* Lazy Load - jQuery plugin for lazy loading images * * Copyright (c) 2007-2015 Mika Tuupola * * Licensed under the MIT license: * http://www.opensource.org/licenses/mit-license.php * * Project home: * http://www.appelsiini.net/projects/lazyload * * Version: 1.9.7 * */ (function($, window, document, undefined) { var $window = $(window); $.fn.lazyload = function(options) { var elements = this; var $container; var settings = { threshold : 0, failure_limit : 0, event : "scroll", effect : "show", container : window, data_attribute : "original", skip_invisible : false, appear : null, load : null, placeholder : "data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAYAAAAfFcSJAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsQAAA7EAZUrDhsAAAANSURBVBhXYzh8+PB/AAffA0nNPuCLAAAAAElFTkSuQmCC" }; function update() { var counter = 0; elements.each(function() { var $this = $(this); if (settings.skip_invisible && !$this.is(":visible")) { return; } if ($.abovethetop(this, settings) || $.leftofbegin(this, settings)) { /* Nothing. */ } else if (!$.belowthefold(this, settings) && !$.rightoffold(this, settings)) { $this.trigger("appear"); /* if we found an image we'll load, reset the counter */ counter = 0; } else { if (++counter > settings.failure_limit) { return false; } } }); } if(options) { /* Maintain BC for a couple of versions. */ if (undefined !== options.failurelimit) { options.failure_limit = options.failurelimit; delete options.failurelimit; } if (undefined !== options.effectspeed) { options.effect_speed = options.effectspeed; delete options.effectspeed; } $.extend(settings, options); } /* Cache container as jQuery as object. */ $container = (settings.container === undefined || settings.container === window) ? $window : $(settings.container); /* Fire one scroll event per scroll. Not one scroll event per image. */ if (0 === settings.event.indexOf("scroll")) { $container.bind(settings.event, function() { return update(); }); } this.each(function() { var self = this; var $self = $(self); self.loaded = false; /* If no src attribute given use data:uri. */ if ($self.attr("src") === undefined || $self.attr("src") === false) { if ($self.is("img")) { $self.attr("src", settings.placeholder); } } /* When appear is triggered load original image. */ $self.one("appear", function() { if (!this.loaded) { if (settings.appear) { var elements_left = elements.length; settings.appear.call(self, elements_left, settings); } $(" ") .bind("load", function() { var original = $self.attr("data-" + settings.data_attribute); $self.hide(); if ($self.is("img")) { $self.attr("src", original); } else { $self.css("background-image", "url('" + original + "')"); } $self[settings.effect](settings.effect_speed); self.loaded = true; /* Remove image from array so it is not looped next time. */ var temp = $.grep(elements, function(element) { return !element.loaded; }); elements = $(temp); if (settings.load) { var elements_left = elements.length; settings.load.call(self, elements_left, settings); } }) .attr("src", $self.attr("data-" + settings.data_attribute)); } }); /* When wanted event is triggered load original image */ /* by triggering appear. */ if (0 !== settings.event.indexOf("scroll")) { $self.bind(settings.event, function() { if (!self.loaded) { $self.trigger("appear"); } }); } }); /* Check if something appears when window is resized. */ $window.bind("resize", function() { update(); }); /* With IOS5 force loading images when navigating with back button. */ /* Non optimal workaround. */ if ((/(?:iphone|ipod|ipad).*os 5/gi).test(navigator.appVersion)) { $window.bind("pageshow", function(event) { if (event.originalEvent && event.originalEvent.persisted) { elements.each(function() { $(this).trigger("appear"); }); } }); } /* Force initial check if images should appear. */ $(document).ready(function() { update(); }); return this; }; /* Convenience methods in jQuery namespace. */ /* Use as $.belowthefold(element, {threshold : 100, container : window}) */ $.belowthefold = function(element, settings) { var fold; if (settings.container === undefined || settings.container === window) { fold = (window.innerHeight ? window.innerHeight : $window.height()) + $window.scrollTop(); } else { fold = $(settings.container).offset().top + $(settings.container).height(); } return fold <=$ (element).offset().top - settings.threshold; }; $.rightoffold=f unction(element, settings) { var fold; if (settings.container===u ndefined || settings.container===w indow) { fold=$ window.width() + $window.scrollLeft(); } else { fold=$ (settings.container).offset().left + $(settings.container).width(); } return fold <=$ (element).offset().left - settings.threshold; }; $.abovethetop=f unction(element, settings) { var fold; if (settings.container===u ndefined || settings.container===w indow) { fold=$ window.scrollTop(); } else { fold=$ (settings.container).offset().top; } return fold>= $(element).offset().top + settings.threshold + $(element).height(); }; $.leftofbegin = function(element, settings) { var fold; if (settings.container === undefined || settings.container === window) { fold = $window.scrollLeft(); } else { fold = $(settings.container).offset().left; } return fold >= $(element).offset().left + settings.threshold + $(element).width(); }; $.inviewport = function(element, settings) { return !$.rightoffold(element, settings) && !$.leftofbegin(element, settings) && !$.belowthefold(element, settings) && !$.abovethetop(element, settings); }; /* Custom selectors for your convenience. */ /* Use as $("img:below-the-fold").something() or */ /* $("img").filter(":below-the-fold").something() which is faster */ $.extend($.expr[":"], { "below-the-fold" : function(a) { return $.belowthefold(a, {threshold : 0}); }, "above-the-top" : function(a) { return !$.belowthefold(a, {threshold : 0}); }, "right-of-screen": function(a) { return $.rightoffold(a, {threshold : 0}); }, "left-of-screen" : function(a) { return !$.rightoffold(a, {threshold : 0}); }, "in-viewport" : function(a) { return $.inviewport(a, {threshold : 0}); }, /* Maintain BC for couple of versions. */ "above-the-fold" : function(a) { return !$.belowthefold(a, {threshold : 0}); }, "right-of-fold" : function(a) { return $.rightoffold(a, {threshold : 0}); }, "left-of-fold" : function(a) { return !$.rightoffold(a, {threshold : 0}); } }); })(jQuery, window, document);